The miner-bcmembers tool

This utility generates revised coexpression clusters from a gene expression file.

You can see the tool’s available options when you enter miner-bcmembers -h at the command prompt:

usage: miner-bcmembers [-h] expfile mapfile regulons outdir

miner-bcmembers - MINER compute bicluster membership inference

positional arguments:
  expfile     input matrix
  mapfile     identifier mapping file
  regulons    regulons.json file from miner-mechinf
  outdir      output directory

optional arguments:
  -h, --help  show this help message and exit

Parameters in detail

miner-bcmembers expects at least these 4 arguments:

  • expfile: The gene expression file a matrix in csv format.
  • mapfile: The gene identifier map file.
  • regulons: The regulons.json file generated by the miner-mechinf tool.
  • outdir: The directory where the result files will be placed in.

Output in detail

After successful completion there will be the following files in the output directory

  • coherentMembers.csv
  • overExpressedMembers.csv
  • underExpressedMembers.csv
  • dysregulatedMembers.csv
  • overExpressedMembers.json
  • underExpressedMembers.json